Professor Basil Sharrack is Consultant Neurologist and Honorary Professor of Clinical Neurology at the Royal Hallamshire Hospital, Sheffield. His main areas of interest are neuro-inflammation and degeneration in MS, therapeutic clinical trials in MS, autologous haematopoietic stem cell transplantation (AHSCT) and cognitive rehabilitation for people with MS, and idiopathic intracranial hypertension.

Basil has authored over 90 peer reviewed original articles and received over £8 million in grants and income from commercial clinical trials. He plays a leading role in the design and conduct of MS clinical trials in the UK, which include the first gene therapy trial at Sheffield Teaching Hospitals NHS Foundation Trust and the first phase III AHSCT treatment in patients with MS. Funding sources are the MS Society, National Institute of Health Research, and Biogen.

KPS Nair is a Consultant Neurologist with a special interest in disability management at Sheffield teaching Hospitals NHS Foundation Trust and a Honorary Senior Lecturer in University of Sheffield. His primary interest is in management of neurological impairments in people with multiple sclerosis. He also has a special interest in palliative care interventions for people with long term neurological conditions. He is involved in imparting training in Neurology and Neurorehabilitation. His research interests include sensory stimulation, gait, spasticity and fatigue in multiple sclerosis.

NIHR Devices for Dignity MedTech Co-operative (D4D) operates nationally, bringing together the optimal team of expert clinicians, academics, members of the public, carers, charities and industry to deliver solutions to address specific needs.

Philippa leads on industry engagement and building strategic relationships with national partners to support D4D's programme portfolio. Philippa manages the Long-Term Neurological Conditions Theme, providing multi-stakeholder project management expertise, leading on strategic funding applications to accelerate collaborations, validating unmet needs through proof of market research, and facilitating the development of commercialisation strategies.

David Paling is currently a Consultant Neurologist at the Royal Hallamshire Hospital, Sheffield, visiting Consultant Neurologist at Doncaster Royal Infirmary, honorary Senior Lecturer at the University of Sheffield and clinical lead for the MS Centre, Sheffield.

David’s clinical training was in Manchester and Queen Square London where he completed a PhD under the supervision of Dr Kapoor and Prof Miller in novel MRI imaging techniques in patients with progressive MS.

His current research interests include integrating MRI into clinical practise, novel imaging techniques in patients with progressive MS, technology aided assessment of disability, MS symptom management and clinical trials.

Sean White, Home Enteral Feed Dietitian at Sheffield Teaching Hospitals NHS Foundation Trust. He has special interest in the decision making process taken by patients and supporting clinical teams prior to gastrostomy placement for long-term enteral feeding in the primary care setting. Sean has presented on many issues relating to home enteral feeding at local and national educational events and conferences. He has also written articles in professional publications and published research focusing on the decision to commence long-term enteral feeding.

Sherif El-Khamisy is a pharmacist who, for the last 20 years, has been fascinated by how cells maintain their genomic integrity. His lab studies this process to come up with new strategies to improve human health and fight disease. His lab uses multidisciplinary approach fusing genetics, chemistry and biology with clinical expertise. The work led to discovery of novel genetic pathways, influenced healthcare practice and developed new technologies. His early work demonstrated a role for PARP1 and CK2 during chromosomal single-strand break repair.

El-Khamisy then moved into more clinical aspects, which led to the identification, for the first time, of a defect in single-strand break repair in two human neurological disorders .

Alasdair's research interest focuses on the genetic cause(s) of neurological disorders, in children and adults. In recent years work in my group has identified novel neurogenetic syndromes associated with variants in the SOX4, SOX11, MYT1L and SLC12A2 genes.

In adults, my interest centres on studying the early (prodromal) stages of neurodegenerative disease using carriers of genetic mutations. We have used gait analysis and wearable sensors to identify preclinical motor changes in pre-symptomatic mutation carriers (22q11 deletion, genetic ataxias).